While the weird, wild, and unusual conditions that affect our pediatric patients deserve our attention, traumatic injuries unquestionably demand much of our clinical attention. We have certainly discussed many trauma topics previously (ex, Abdominal Trauma, Aortic Trauma, Damage Control Resuscitation, Dental Trauma), but the one region of the body that, when injured, leads to the most significant problem is the head. While much of the time we are afforded the opportunity to discuss limiting medical radiation in the setting of Minor Head Injury, there are times when it isn’t a minor problem. Let us take a minute to ensure we are taking simple steps to help those with Major Traumatic Brain Injury:
Not Minor. TBI is a Major Problem!
In the USA, traumatic brain injury (TBI) leads to > $1 billion in total hospital charges annually. [Schneier, 2006]
Adolescents develop TBI primarily from motor vehicle collisions.
Younger children are exposed to TBI often from falls.
Much of the work done for pediatric closed head injury has focused on how to risk stratify those who have had minor head impacts and are at Low Risk for having a substantial intracranial injury. While this is important, Major Traumatic Brain Injury is devastating and we need to know some basic steps to help these patients.
Primary Injury vs Secondary Injury
The primary insult (ex, blunt impact, penetrating missile, blast, rapid acceleration-deceleration) can create a severe injury.
Some will lead to Epidural or Subdural hematomas that warrant neurosurgical intervention.
Some will lead to irreversible damage (ex, Diffuse Axonal Injury).
The secondary insult evolves as a consequence of the primary insult and is what clinicians need to be mindful to prevent.
The injured brain is very susceptible to additional injury.
Hypotension and/or hypoxia will further stress the tenuous regions around the primary injury.
Prevent Hypotension and Hypoxemia.
Both will worsen secondary brain injury.
RSI with C-Spine stabilization should be done early.
Head of Bed at 30 degrees will aid in venous drainage.
Ensure head is Midline to ensure one side’s venous flow is not being constricted.
Avoid additional physiologic stressors that can increase mortality risk! [Smith, 2012; Davis, 2009; McHugh, 2007]
Avoid Hyperthermia
Avoid Hypoglycemia and Hyperglycemia
Avoid Hypocapnea
Avoid Hyperoxia
Make the patient sedated and paralyzed!
The patient fighting and struggling will increase ICP.
Agitation, anxiety and stress will all exacerbate the problem.
Be mindful, though, of inducing hypotension.
Consider Etomidate if lower BPs
Ketamine has also been shown to be safe for patients with TBI. [Bar-Joseph, 2009].
Thiopental is an alternative for patients who have higher BPs.
Many will choose to use Lidocaine as a pretreatment medication for RSI.
Good idea… but really needs to be given several minutes before intubation.
If you have time to use it, feel free to. If you don’t, don’t waste time waiting for it. {that’s my 2 cents}
Moral of the Morsel
While avoiding unnecessary CT in patients with Low Risk for significant traumatic brain injury is important, remembering to do some rather basic steps is crucial for our patients who have major TBI!
Basics are Best! Check that Head of Bed angle.
Keep that ICP low and that BP normal! Cerebral Perfusion depends on it!
Bar-Joseph G1, Guilburd Y, Tamir A, Guilburd JN. Effectiveness of ketamine in decreasing intracranial pressure in children with intracranial hypertension. J Neurosurg Pediatr. 2009 Jul;4(1):40-6. PMID: 19569909. [PubMed] [Read by QxMD]
Deepening sedation is often needed in patients with intracranial hypertension. All widely used sedative and anesthetic agents (opioids, benzodiazepines, propofol, and barbiturates) decrease blood pressure and may therefore decrease cerebral perfusion pressure (CPP). Ketamine is a potent, safe, rapid-onset anesthetic agent that does not decrease blood pressure. However, ketamine’s use in patients with traumatic brain injury and intracranial hypert […]
Davis DP1, Meade W, Sise MJ, Kennedy F, Simon F, Tominaga G, Steele J, Coimbra R. Both hypoxemia and extreme hyperoxemia may be detrimental in patients with severe traumatic brain injury. J Neurotrauma. 2009 Dec;26(12):2217-23. PMID: 19811093. [PubMed] [Read by QxMD]
An association between hypoxemia and poor outcomes from traumatic brain injury (TBI) is well documented. However, it is unclear whether hyperoxygenation is beneficial. This registry-based analysis explores the relationship between early hypoxemia and hyperoxemia on outcome from moderate-to-severe TBI. TBI patients (Abbreviated Injury Scale score 3+) were identified from the San Diego County trauma registry. Patients were stratified by arrival par […]
McHugh GS1, Engel DC, Butcher I, Steyerberg EW, Lu J, Mushkudiani N, Hernández AV, Marmarou A, Maas AI, Murray GD. Prognostic value of secondary insults in traumatic brain injury: results from the IMPACT study. J Neurotrauma. 2007 Feb;24(2):287-93. PMID: 17375993. [PubMed] [Read by QxMD]
We determined the relationship between secondary insults (hypoxia, hypotension, and hypothermia) occurring prior to or on admission to hospital and 6-month outcome after traumatic brain injury (TBI). A meta-analysis of individual patient data, from seven Phase III randomized clinical trials (RCT) in moderate or severe TBI and three TBI population-based series, was performed to model outcome as measured by the Glasgow Outcome Scale (GOS). Proporti […]
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[…] The time of year certainly affects what conditions we must consider when caring for children (ex, Traumas, Submersion Injuries, Bronchiolitis) and when it is cold outside, people do what they need can in […]